Search results for "nociceptive withdrawal reflex"

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The Effects of Transcutaneous Spinal Direct Current Stimulation on Neuropathic Pain in Multiple Sclerosis: Clinical and Neurophysiological Assessment

2019

Background: Central neuropathic pain represents one of the most common symptoms in multiple sclerosis (MS) and it seriously affects quality of life. Spinal mechanisms may contribute to the pathogenesis of neuropathic pain in MS. Converging evidence from animal models and neurophysiological and clinical studies in humans suggests a potential effect of transcranial direct current stimulation (tc-DCS) on neuropathic pain. Spinal application of DCS, i.e., transcutaneous spinal DCS (ts-DCS), may modulate nociception through inhibition of spinal reflexes. Therefore, ts-DCS could represents an effective, safe and well-tolerated treatment for neuropathic pain in MS, a largely unexplored topic. This…

transcutaneous spinal direct current stimulation (ts-DCS)nociceptive withdrawal reflexmedicine.medical_treatmentnon-invasiveWithdrawal reflexmultiple sclerosis050105 experimental psychologylcsh:RC321-57103 medical and health sciencesBehavioral Neuroscience0302 clinical medicinemedicine0501 psychology and cognitive sciencesSpasticitylcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological PsychiatryOriginal Researchneuropathic painTranscranial direct-current stimulationbusiness.industryMultiple sclerosis05 social sciencesmedicine.diseaseNeuromodulation (medicine)Psychiatry and Mental healthNeuropsychology and Physiological PsychologyNociceptionNeurologyAnesthesianeuromodulationNeuropathic painmultiple sclerosis; neuromodulation; neuropathic pain; nociceptive withdrawal reflex; non-invasive; transcutaneous spinal direct current stimulation (ts-DCS)Reflexmedicine.symptombusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Human Neuroscience
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